PANTHENOL B5

Panthenol (also known as Provitamin B5), one of the most versatile and widely used molecules in dermatology and cosmetics.

🔬 Scientific Background & Mechanisms

  • Panthenol = Provitamin B5 → once absorbed by the skin, it is converted into Pantothenic Acid, an essential component of Coenzyme A (CoA).
  • CoA is crucial for cellular metabolism, energy production, and lipid synthesis, especially in skin barrier repair.
  • Exists in D- and DL- forms → D-Panthenol is biologically active and most effective in skincare.

🌟 Comprehensive Skin Benefits

1. Moisturizing & Hydration Booster

  • Humectant → attracts and binds water molecules in the skin.
  • Improves stratum corneum hydration → skin feels softer, smoother, and more supple.
  • Reduces transepidermal water loss (TEWL).

2. Barrier Repair & Strengthening

  • Stimulates synthesis of lipids and essential proteins.
  • Accelerates recovery of a compromised skin barrier.
  • Helps skin resist irritants, allergens, and environmental stressors.

3. Soothing & Anti-Inflammatory

  • Reduces erythema (redness), itching, and irritation.
  • Calms sensitive, inflamed, or reactive skin.
  • Particularly effective in eczema, dermatitis, and post-procedure care.

4. Healing & Regeneration

  • Speeds up cell proliferation and tissue repair.
  • Promotes wound healing and scar reduction.
  • Widely used in after-sun care, burns, cuts, and abrasions.

5. Anti-Aging Support

  • By strengthening the barrier and improving hydration, it reduces fine lines caused by dehydration.
  • Improves skin softness and elasticity over time.

6. Compatibility & Safety

  • Extremely gentle and well tolerated by all skin types (including sensitive and baby skin).
  • Non-comedogenic, non-irritant, and hypoallergenic.
  • Can be combined with virtually all other active ingredients.

💊 Dermatological & Cosmetic Applications

  • Moisturizers and creams → hydration and repair.
  • Soothing lotions → for sensitive or irritated skin.
  • After-sun and burn care → accelerates healing and calms redness.
  • Wound-healing ointments → for cuts, abrasions, and post-procedure care.
  • Baby skincare products → diaper rash creams, gentle cleansers.
  • Hair care (shampoos, conditioners, masks):
    • Improves hair elasticity and softness.
    • Reduces breakage and split ends.
    • Adds shine and moisture.

🔗 Best Synergies

  • Hyaluronic Acid & Glycerin → enhances hydration.
  • Niacinamide → combines barrier repair + soothing + brightening.
  • Allantoin & Madecassoside → synergistic calming and healing effect.
  • Ceramides & Fatty Acids → stronger barrier repair.
  • Aloe Vera → cooling + soothing in after-sun or irritation care.

✅ Summary

Panthenol is a powerful, safe, and multi-functional skincare molecule with:

  • Moisturizing & barrier repair properties
  • Soothing & anti-inflammatory action
  • Healing & regenerative benefits
  • Hair-strengthening & conditioning effects
  • Exceptional tolerability for all skin types

👉 It’s one of the gold-standard soothing and repairing ingredients, making it a must-have for hydration, sensitivity, wound care, and hair health.