GLUCONOLACTONE

Gluconolactone (PCA Gluconolactone)

🔬 Scientific Background & Mechanisms

  • Gluconolactone is a polyhydroxy acid (PHA), derived from glucose.
  • Water-soluble, gentle molecule with multiple hydroxyl groups → acts as a humectant and very mild exfoliant.
  • Forms a lactone that converts to gluconic acid upon contact with water.
  • Capable of chelating metal ions and providing antioxidant protection.

🌟 Comprehensive Skin Benefits

  1. Hydration & Moisture Retention
    • Natural humectant → attracts and binds water in the epidermis.
    • Improves skin softness, smoothness, and comfort.
  2. Gentle Exfoliation & Smoothing
    • Stimulates cellular turnover without irritation.
    • Reduces the appearance of fine lines, rough texture, and uneven skin.
    • Better tolerated than traditional AHAs (glycolic acid, lactic acid) for sensitive skin.
  3. Anti-Aging & Antioxidant Effect
    • Neutralizes free radicals → protects against oxidative stress.
    • Improves skin elasticity and firmness over time.
  4. Soothing & Suitable for Sensitive Skin
    • Reduces mild redness and irritation.
    • Ideal for reactive or sensitive skin types.
  5. Barrier Support
    • Maintains the integrity of the stratum corneum.
    • Promotes soft, comfortable, and hydrated skin.

💊 Dermatological & Cosmetic Applications

  • Anti-aging and hydrating serums
  • Creams for sensitive skin
  • Gentle exfoliating masks and lotions
  • Post-procedure or after-sun care products

⚖️ Typical Concentrations

  • 1–15% depending on desired effect (hydration or gentle exfoliation).
  • Well tolerated even on sensitive skin.

🔗 Best Synergies

  • Hyaluronic Acid & Glycerin → maximizes hydration
  • Niacinamide → barrier support + smoothing
  • Antioxidants (Vitamin C, Resveratrol) → protection and regeneration
  • Peptides & Ceramides → enhance elasticity and barrier function

✅ Summary
Gluconolactone is a gentle, hydrating, and anti-aging cosmetic ingredient:

  • Humectant → long-lasting hydration
  • Very mild exfoliant → smooth, even skin
  • Antioxidant → protection against free radicals
  • Suitable for sensitive and reactive skin