HYALURONIC ACID
Hyaluronic Acid (HA)
🔬 Scientific Background & Mechanisms
- Hyaluronic Acid is a naturally occurring glycosaminoglycan found in the extracellular matrix of skin, connective tissues, and joints.
- High molecular weight polysaccharide composed of repeating disaccharide units of glucuronic acid and N-acetylglucosamine.
- Functions as a powerful humectant and skin-conditioning agent, holding water in the skin to maintain volume, elasticity, and hydration.
- Can form a viscoelastic gel in the extracellular matrix, providing structural support and cushioning.
🌟 Comprehensive Skin Benefits
- Intense Hydration & Moisture Retention
- Attracts and retains water up to 1000× its weight.
- Reduces transepidermal water loss (TEWL).
- Keeps skin soft, plump, and supple.
- Plumping & Anti-Wrinkle Effect
- Fills in fine lines and micro-wrinkles caused by dehydration.
- Restores skin volume and smoothness for a youthful appearance.
- Barrier Support & Protection
- Strengthens the skin’s natural barrier.
- Protects against environmental aggressors, oxidative stress, and dryness.
- Healing & Tissue Regeneration
- Supports skin repair and tissue regeneration.
- Speeds up recovery of damaged or stressed skin.
- Compatibility & Safety
- Non-irritating, non-comedogenic, suitable for all skin types.
- Can be combined with almost all other cosmetic active ingredients.
💊 Dermatological & Cosmetic Applications
- Hydrating serums and moisturizers
- Anti-aging creams and gels
- Facial masks and sheet masks
- Post-procedure or after-sun care products
⚖️ Typical Concentrations
- 0.1–2% for hydration and plumping effects in cosmetics.
- Can be combined with lower molecular weight fragments (e.g., Hydrolyzed Hyaluronic Acid) for deeper penetration.
🔗 Best Synergies
- Sodium Hyaluronate & Hydrolyzed Hyaluronic Acid → multi-layered hydration
- Glycerin & Propanediol → enhanced humectant effect
- Niacinamide & Peptides → barrier repair + anti-aging synergy
- Antioxidants → protection against oxidative stress
✅ Summary
Hyaluronic Acid is a versatile and highly effective skincare molecule:
- Powerful humectant → long-lasting hydration
- Plumping effect → reduces fine lines and improves skin smoothness
- Supports skin barrier → protects and soothes
- Safe for all skin types and compatible with most cosmetic actives